Nafgal 2% Cream 10gm

Uses of Naftifine

• Skin fungal infections
• Treatment of interdigital tinea pedis, tinea cruris, and tinea corporis

Instructions for Use:

1. Clean and dry the affected area thoroughly before application.
2. Apply a thin layer of the cream or gel to the affected area and the surrounding skin.
3. Wash your hands after applying the cream or gel, unless you are treating your hands.
4. Continue using the cream or gel for the full treatment period, even if symptoms improve earlier, to prevent the recurrence of the infection.

Side Effects of Naftifine

The most common side effect is pruritus (itching).

Quick Suggestions:

• Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
• In wet places such as changing rooms and gym showers, avoid walking barefoot to prevent fungal infections.
• Do not scratch the affected area of the skin, as it can spread the infection to other body parts.
• Avoid sharing towels, combs, bedsheets, shoes, or socks with others.
• Wash your bedsheets and towels regularly.
• Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Indications:

Nafgal Cream is a synthetic, broad-spectrum antifungal agent and allylamine derivative. It shows fungicidal activity against a broad spectrum of organisms such as Trichophyton species and fungistatic activity against Candida species including Candida albicans. However, it is used specifically to treat the organisms listed in the indications.

Pharmacology

Nafgal Cream interferes with sterol biosynthesis by inhibiting the enzyme squalene 2,3-epoxidase. This results in decreased amounts of sterols, especially ergosterol, and an accumulation of squalene in the cells, which disrupts fungal cell membranes.

Dosage & Administration of Naftifine

Adults:

• Form: Cream or Gel
• Application:
  • Cream: Apply a sufficient amount of Nafgal Cream once daily.
  • Gel: Apply a sufficient amount twice daily, in the morning and evening.
• Duration of Treatment:
  • Tinea cruris (jock itch): 2-4 weeks
  • Tinea corporis (ringworm): 2-4 weeks
  • Tinea pedis (athlete's foot): 4-6 weeks
  • Severe infections: May require prolonged treatment.

Do not use it for ophthalmic, oral, or intravaginal purposes.

The safety and effectiveness of Nafgal Cream have been established in patients aged 12-17 with interdigital tinea pedis and tinea cruris. Its safety and effectiveness in pediatric patients under 12 years of age have not been established.

Interaction

No interactions were found or established.

Contraindications

Do not use Naftifine if you are allergic to any of its components. 

Pregnancy & Lactation

Pregnancy Category B. There are no adequate and well-controlled studies of Naftifine Cream in pregnant women. Because animal reproduction studies are not always predictive of human response, Naftifine Cream should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Nursing Mothers: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Naftifine Cream is administered to a nursing woman.

Precautions:

• Naftifine is for external use only; do not swallow it.
• Avoid contact with the mouth, nose, and eyes.
• In case of accidental contact, wash the area thoroughly with water and inform your doctor for further treatment.
• Consult the doctor if you are pregnant or breastfeeding.
• Let the doctor know if you are using any other medicines, including supplements and herbal products.

Storage Conditions:

Store Nafgal Cream at 25°C, with permitted excursions between 15-30°C.